Background of the project:
Charcot Neuropathic Osteoarthropathy of the Foot in Diabetes is known to be a severe complication of the disease. Although a number of circulating blood cytokines and inflammatory markers have been described, how these can be used to monitor progress of resolution, and how these correlate with changes seen on imaging is uncertain. The gold standard of management is non-removable offloading of the affected limb, but as resolution of the acute Charcot is poorly defined, uncertainty remains about the length of treatment.
The DFSG is now initiating a group of young academics/clinicians/scientists to work on the field of “Charcot Neuropathic Osteoarthropathy of the Foot in Diabetes: monitoring of evolution and resolution” with the aim to develop a grant application to investigate the above.
The Executive Committee of DFSG has agreed to support the project with a grant, which will be used to bring the group together a few times, as we feel it is valuable to meet eye to eye for maximum commitment and inspiration.
Notifications will be sent to all applicants in early June 2021.
Once applicants have been selected, the group will meet to discuss different circulating blood cytokines, inflammatory markers and imaging with a view to a future longitudinal study to further define the evolution and resolution of an acute Charcot foot in Diabetes.
The value-based agenda will be used to define potential markers for future grant application to test the hypotheses developed
Nina Petrova, UK
Anna Korzon, PL
Alexandra Jirkovska, CZ
Armin Koller, DE
Frances Game, UK